The Tender Hurt of Iranian Sensibilities
Surely
the leader of such an important, UN-prestigious country like the
Islamic Republic of Iran is entitled to his considered opinion, much
less to savouring the attention that the world community of democracies
lavishes upon his glorious administration's need to reassure the
pathetic concerns that attend nuclear proficiency.
Iran is indubitably at the crest of those nations wishing to convince irredentist nations that they have an obligation to let sleeping dogs bark, but not bite. Israel is a dog with a loud bark but a nasty bite. It urgently requites euthanization, and Iran has generously allowed itself to be persuaded to execute that little favour on behalf of world peace.
Perhaps not by nuclear annihilation, although the very concept is undeniably appealing, but simply by withholding from the Zionist Entity the approval of the kind and gentle Iranian ayatollahs of the impossibly racist occupation by the Zionist Devils of land consecrated to Islam, and requiring to be possessed in perpetuity by Muslims.
Canada has erred, seriously, in delisting the adversarial group Mujahedihn-e-Khalq as a terrorist group. And horrors! replacing that exiled Iranian group that challenges the legitimacy - let alone sanity of the current administration of Iran, with the inclusion of the Quds branch of the Islamist National Republican Guard. Clearly those Canadians are mad as hatters.
Do they all sniff glue?
Iran's foreign ministry's statement makes it abundantly clear how much of an outlier Canada is within the international community by
"using the issue of terrorism as a tool and violating its international commitments" by this horrendous move to demonize the legitimate and honoured Republic and the Republican Guard.
This move by Canada becomes explicable when one recalls it to be a lackey of the Byzantine America, the foremost hater of Iran and itself a dismal lackey of the archdeacon of the devil, Israel. For the United States preceded Canada in claiming that the Quds Force and the Iranian Revolutionary Guard Corps are involved in nurturing and committing terrorist acts.
Canada, furthermore, by claiming that the Quds Force funds and trains foreign extremists is engaged in unwholesome slander, and shame on them. But then, Canada is beyond shame, it is utterly shameless; witness its expulsion of Iranian diplomats from Canada, their absurd explanation being that Iran sponsors terrorism.
The Quds Force supporting the Taliban, Hezbollah, Hamas, Palestinian Islamic Jihad and the Popular Front for the Liberation of Palestine? Only the stupidity of the Western mind could possibly conflate these honourable resistance militias with terror. They have all been elevated to a honoured status as martyrs-in-waiting in the divine service of Islam.
The resolution that Canada led in the United Nations General Assembly denouncing what they alleged to be human rights abuses within the Islamic Republic of Iran was an absolute farce, a horrible misuse of the United Nations, a shameful parody of justice, despite their lofty statements to the contrary.
While Canadian counter-terror units concern themselves with the abduction of Canadian aboriginal children to alter their minds and produce of them citizens of a racist state suitable for trafficking out to other countries with dismal human rights records, to earn profits for the country, Iran is generously sending its gays to Canada, saving state funds that might otherwise be wasted in hanging them.
What the West fails to realize is that this is all a matter of perspective, and theirs is gruesomely incorrect.
Labels: Canada, Crisis Politics, Human Rights, Iran, Islamism, Israel, United States
. Report: 150 Corpses Found in Syrian School
by Gil Ronen
- Arutz Sheva 7
At least 150 charred corpses were
found Saturday in Deir Baalba in Homs, Syria, according to a report by the Shaam
Network that was quoted in Al Arabiya.
Earlier Saturday, Syrian regime
forces killed 20 people in a town near Aleppo. Eighty other people were killed
nationwide, according to opposition Coordination Committees.
Sana
Revolution reported that a “massacre” took place in Khamsya, near Aleppo.
The fighting in Aleppo forced Syrian Air, Syria’s national airline, to
cancel a flight to the city. According to Cairo airport officials, a flight that
was supposed to stop in Aleppo before continuing to Damascus flew straight to
Damascus “because of the deteriorated security situation” near the Aleppo
airport.
The Al Arabiya report stated that this was the first time a
flight to Aleppo had been canceled because of fighting. The Syrian government
and its airline did not comment.
Syria rebels have launched a campaign
to seize government airports as a way to cut the regime’s supply lines and
strike a blow against its air power, the biggest threat faced by the
insurrection.
Labels: Political Realities, Revolution, Security, Societal Failures, Syria
Abbas Makes It Official: All of Israel is Palestine
by Tzvi Ben
Gedalyahu
- Arutz Sheva 7
The Fatah party, headed by
Palestinian Authority Chairman Mahmoud Abbas, has made official what it has been
saying quietly and has adopted a new logo showing all of Israel as Palestine.
The logo marks the 48th anniversary of the founding of Fatah by Yasser
Arafat and includes a map with the PA flag and a map of Israel that appears to
be a depiction of the black and white checkered kefiyah, a symbol of the violent
intifada, and the slogan “the state and victory."
Palestine Media Watch
(PMW) revealed that the official PA daily published the new official logo.
For the past year, official PA documents have increasingly shown
Palestine as covering all of Israel, but this is the first time the Fatah party
has placed the map on its logo.
PMW noted, “Other symbols central to
Fatah ideology also appear in the logo, including a rifle and a key symbolizing
the Palestinian claim of ownership to houses within Israel.”
The Arab
media watchdog translated and published the article announcing the new logo:
"Senior Fatah official in the Gaza Strip, Yahya Rabah, stressed that the
movement this year will hold a big, central rally in the Gaza Strip on the day
of the 48th anniversary of the beginning of the Palestinian revolution.
“Rabah explained to Ma'an that the event will be held considering the
atmosphere of reconciliation and unity that has prevailed in the Palestinian
arena in the last few….
“The organizing committee for the 48th
anniversary of the Fatah movement approved this year's main anniversary logo...
[The rally] will take place in Gaza to mark the 48th anniversary of the modern
Palestinian revolution under the slogan 'the state and the victory.'"
The Zionist Organization of America (ZOA) reacted to the new logo by
urging “President Barack Obama, the European Union and the United Nations to
condemn this outrage which reiterates the clear fact that Abbas and the Fatah/PA
have no interest in peace with Israel, only its destruction.”
ZOA National President Morton A. Klein said, "This new Fatah
logo graphically depicts the ugly truth about this unreconstructed terrorist
organization whose Constitution to this day calls for the destruction of Israel
(Article 13) and the use of terrorism as an essential element in the struggle to
achieve this aim (Article 19). …It belies the fiction that Mahmoud Abbas is a
'moderate' who seeks peace with Israel, and who wishes to end Palestinian
terrorism against Israeli Jews. It also makes clear that the principles of
Yasser Arafat are respected and promoted.
"The new Fatah logo is
not an aberration. The Palestinian Authority continues to promote the incitement
of hatred in Palestinian mosques, schools and media.
"The ZOA
renews its call upon the Obama Administration to stop wasting hundreds of
millions of dollars on the unreformed terrorist entity that is Fatah, to stop
making excuses for Abbas, and to stop pressuring Israel to make dangerous
concessions on the altar of appeasement.”
Labels: Heritage, Islamism, Israel, Palestinian Authority, Political Realities
Indian gang-rape victim planned to marry man attacked alongside her, friends reveal
Mahesh Kumar / AP
Indian students shout slogans during
a protest rally in Hyderabad, India, Monday, Dec. 31, 2012. The
gang-rape and killing of a New Delhi student has set off an impassioned
debate about what India needs to do to prevent such a tragedy from
happening again. The country remained in mourning Monday, two days after
the 23-year-old physiotherapy student died from her internal wounds in a
Singapore hospital.
The Indian woman who was brutally
gang raped and later died of her injuries was cremated Sunday, as her
friends revealed she was engaged to marry the man attacked alongside
her.
The pair were to be married in February,
The Telegraph reported.
“They had made all the wedding preparations and had planned a wedding
party in Delhi,” said Meena Rai, a friend and neighbour told the
newspaper. “I really loved this girl. She was the brightest of all.”
India remained in mourning Monday, two days after the 23-year-old
physiotherapy student died from her internal wounds in the Singapore
hospital where she had been sent for emergency treatment. Six men have
been arrested and charged with murder in the Dec. 16 attack on a New
Delhi bus. They face the death penalty if convicted, police said.
Sajjad Hussain / AFP / Getty ImagesIndian
protesters light candles around a mannequin representing the rape
victim during a rally in New Delhi on December 31, 2012. The family of
an Indian gang-rape victim said they would not rest until her killers
are hanged as they spoke of their own pain and trauma over a crime that
has united the country in grief.
The country’s army and navy also cancelled New Year’s celebrations
out of respect for the woman, whose gang-rape and murder has set off an
impassioned debate about what the nation needs to do to prevent such a
tragedy from happening again.
Protesters and politicians have called for tougher rape laws, major
police reforms and a transformation in the way the country treats its
women.
“To change a society as conservative, traditional and patriarchal as
ours, we will have a long haul,” said Ranjana Kumari, director of the
Center for Social Research. “It will take some time, but certainly there
is a beginning.”
“She has become the daughter of the entire nation,” said Sushma Swaraj, a leader of the opposition Bharatiya Janata Party.
Hundreds of mourners continued their daily protests near Parliament demanding swift government action.
“So much needs to be done to end the oppression of women,” said
Murarinath Kushwaha, a man whose two friends were on a hunger strike to
draw attention to the issue.
Manish Swarup / AP Indian
members of All India Students' Association (AISA) shout slogans during a
protest in New Delhi, India, Monday, Dec. 31, 2012. The gang-rape and
killing of a New Delhi student has set off an impassioned debate about
what India needs to do to prevent such a tragedy from happening again.
The country remained in mourning Monday, two days after the 23-year-old
physiotherapy student died from her internal wounds in a Singapore
hospital.
Some commentators compared the rape victim, whose name has not been
released by police, to Mohamed Bouazizi, the Tunisian street vendor
whose self-immolation set off the Arab Spring. There was hope her
tragedy could mark a turning point for gender rights in a country where
women often refuse to leave their homes at night out of fear and where
sex-selective abortions and even female infanticide have wildly skewed
the gender ratio.
“It cannot be business as usual anymore,” the Hindustan Times newspaper wrote in an editorial.
Politicians from across the spectrum called for a special session of
Parliament to pass new laws to increase punishments for rapists —
including possible chemical castration — and to set up fast-track courts
to deal with rape cases within 90 days.
The government has proposed creating a public database of convicted
rapists to shame them, and Prime Minister Manmohan Singh has set up two
committees to look into what lapses led to the rape and to propose
changes in the law.
The Delhi government on Monday inaugurated a new helpline — 181 — for women, though it wasn’t working because of glitches.
Responding to complaints that police refuse to file cases of abuse or
harassment brought by women, the city force has appointed an officer to
meet with women’s groups monthly and crack down on the problem, New
Delhi Lt. Gov. Tejendra Khanna said.
“We have mandated that any time any lady visits a police station with a complaint, it has to be recorded on the spot,” he said.
Kumari said the Delhi police commissioner sent her a message Monday
asking her group to restart police sensitivity training that it had
suspended due to lack of funds.
There have also been proposals to install a quota to ensure one-third of Delhi’s police are women.
There also have been signs of a change in the public debate about crimes against women.
Other rapes suddenly have become front-page news in Indian
newspapers, and politicians are being heavily criticized for any remarks
considered misogynistic or unsympathetic to women.
A state legislator from Rajasthan was ridiculed Monday across TV news
channels after suggesting that one way to stop rapes would be to change
girls’ school uniforms to pants instead of skirts.
“How can he tell us to change our clothes?” said Gureet Kaur, a
student protester in the Rajasthani town of Alwar. “Why can’t girls live
freely?”
Some activists have accused politicians of being so cossetted in
their security bubbles that they have no idea of the daily travails
people are suffering.
Kumari said the country was failing in its basic responsibility to
protect its citizens. But she was heartened to see so many young men at
the protests along with women.
“I have never heard so many people who felt so deep down hurt,” she said. “It will definitely have some impact.”
With files from National Post staff
Labels: Crime, Crisis Politics, Culture, Human Relations, India, Security, Sexism, Societal Failures
-
New Constitution divides Egypt as economy falters
The process of passing Egypt's Constitution has created more
political distrust and anger. Meanwhile, a neglected economy is heading
towards grim shoals.
Saddam
Hassan, a protester injured during clashes with Muslim brotherhood
supporters, stands outside his tent near the presidential palace in
Cairo, Egypt, Friday. The official approval of Egypt's disputed,
Islamist-backed constitution held out little hope of stabilizing the
country after two years of turmoil and Islamist President Mohammed Morsi
may now face a more immediate crisis with the economy falling deeper
into distress.
Amr Nabil/AP
New constitutions are usually greeted with great fanfare. They're
assumed to carry both the promise of a fresh start and signal that a
chaotic transition has come to an end.
But
Egypt's new constitution is something else again. Signed into law on Dec. 26 by
President Mohamed Morsi,
the new charter has become a symbol of a sharply divided nation. Mr.
Morsi's opponents charge the passage of the constitution is not the
result of a national consensus, but evidence that the
Muslim Brotherhood that propelled Morsi to power intends to push its agenda over the heads of secular-leaning and liberal political opponents.
While
Morsi extended an olive branch to opponents in a nationally televised
speech on Dec. 26, the country is at its most sharply polarized point
since longtime dictator
Hosni Mubarak
was ousted in February 2011. Egypt is scheduled to hold parliamentary
elections in about two months, and the runup to that election is more
likely to exacerbate Egypt's open political wounds rather than heal
them.
What will that mean? More street protests, more chaotic
governance, and no short-term fixes for an economy that was weak at the
time Mr. Mubarak fell and has gone from bad to worse. The Egyptian pound
fell to its lowest point against the
dollar
in eight years this week, and the currency may say more about what
happens to Egypt in the coming years than the contents of the new
Constitution. Roughly 30 million of Egypt's 80 million people get by on
$2 or less a day, and are heavily reliant on government subsidies. The
Egyptian government spent $3 billion on its subsidized bread program
alone last year.
And with tourism in the dumps and a collapse in local and foreign
investment, the government's ability to meet the most fundamental needs
and demands of its citizens has been badly strained. Foreign reserves
stood at about $36 billion at the start of 2011. Today, foreign reserves
are at about $15 billion.
Finding a solution to Egypt's economic
woes won't be easy. But for now, that issue is being pushed to the side,
with a loose coalition of secular-leaning groups vowing to fight
against the Muslim Brotherhood's agenda. The opposition argues that
individual liberties are now threatened by the enshrining of aspects of
Islamic law into the Constitution and giving Egypt's powerful military
the right to detain and try civilians under some circumstances.
Morsi
promised a national dialogue this week and said "mistakes" were made in
the drafting of the Constitution, but those remarks fell completely
flat as a conciliatory gesture. In the past few weeks he's gotten
everything he wanted and critics of the Constitution received zero
concessions. Now that he has the document in hand, offers of "dialogue"
are being seen as an attempt to put a magnanimous gloss on what was a
bare-knuckle, winner-take-all contest that Morsi and the Muslim
Brotherhood just won.
Leftists, so-called liberals, and Egyptians
who want a secular approach to the state and Egyptian identity are
furious and pondering their next moves. The Brotherhood, meanwhile, is
sticking to the game plan that's made it the winner in all four
elections held (two referendums, the last parliamentary election, and
the presidential) since Mubarak was driven from power in February 2011:
superior organization and on-the-ground mobilization.
While
opponents of the Constitution pointed to low turnout in the referendum
as a sign of general public dissatisfaction with the document, the
Brothers have won both elections with overwhelming turnout and ones with
small turnout. With the constitution set, next up are fresh
parliamentary elections that the movement is going to
pull out all the stops to dominate, just like it did last time.
That
annulled parliamentary election has much to do with why Morsi's
political opponents trust neither him nor his movement. In 2011, the
Brothers loudly proclaimed that they had no intention of dominating
Egyptian politics and vowed to contest only about 30 percent of the
seats in the next parliament. The movement and its newly minted Freedom
and Justice Party (FJP) also promised not to run a candidate for
president.
But as the contours of the new Egypt started to emerge,
and the prospect of a counter-revolution by military officers looked
less likely, the Brothers abandoned both promises. Obviously, Morsi won
the presidency. And as for Parliament, the Brother's contested 100
percent of the seats, winning almost half of them.
Now on Morsi's
agenda is victory in the parliamentary election. If the Brothers can
steamroll the opposition again, they'll hold the presidency, the
legislature, and a Constitution written with little input from the
country's secular-leaning forces.
But the real challenge is
Egypt's weak economy and the increased suffering of its poor. Absent
economic improvement, and soon, the turmoil of Egypt's past two years
could well end up being overshadowed.
Labels: Conflict, Crisis Politics, Egypt, Human Relations, Islamism, Muslim Brotherhood
Op-Ed: Did We Hurt Your Feelings, Israel Bashers? Too Bad
Published: Sunday, December 30, 2012 9:55 PM Arutz Sheva 7
One sided blame, calls for boycotts, questioning
Israel's right to exist - those are common Israel-basher pasttimes.
Why are they complaining?
Dr. Harold Goldmeier
The
writer is a former Research and Teaching Fellow at Harvard University
where he received his doctorate. He served in the administrations of
three U. S. Governors, is a business management consultant with a
personal interest in education and NGOs.
There is
an old expression that says “Don’t spit on me, and tell me it’s
raining.” That is exactly what some Jewish critics of Israeli policy
toward the Palestinians and Arabs do when they cry about being called
anti-Semitic for their
activities and policy positions.
Professor Eva Illouz of the Hebrew
University is the latest to take up the cudgel offended at the reaction she is getting from supporters of Israel. In a recent article in
The Forward,
she lumps herself in with Peter Beinart, Noam Chomsky, Judith Butler,
Avi Shlaim, and Shlomo Sand, for doing “nothing more than (exercising)
the right to think and evaluate critically the accomplishments and
failures of the state of Israel.”
There is too little space
here to document the depths of depraved criticism her fellow travellers
heap on Israel, the one-sided blame they cast, and their calls for
actions against Israel that can only lead to Israel’s defeat and
disappearance. This is the group that the distinguished Professor
proudly claims to be her like-minded colleagues.
I am not being facetious in
calling her
distinguished. Professor Illouz won the Best Book Award prize, and her
works on emotions, culture, and communication are translated into 15
different languages. In fact, all of the people in her clique are
recognized experts in their fields of study. They are international
award-winning intellectuals, and, in other circumstances, Jews over
which we "kvell". However, they put their talents and energies into
exoteric diatribes against the Jewish State without a scintilla of sweat
for her sworn enemies and their murderous agenda.
Chomsky,
son of Hebrew teachers and a former kibbutznik, wages war for decades
against Israel with vile and scurrilous claims. His recurring theme is
that the creation of Israel was “wrong and disastrous.” He regularly
compares Israel’s actions to those of the Nazis.
Butler
preceded Beinart in the boycott, disinvestment, and sanctions campaign
against Israel. She coined the colorful and sympathetic attributions of
Hamas and Hizbullah as progressive and social movements. She is an
executive member of a freedom theatre in Jenin. Its most famous
playwright and director was Juliano Mer-Khanis, gunned down by
Palestinian nationalists. He was driving with his one year old son in
the car when Mafia-like gunmen carried out their death sentence for his
crime of being an Israeli-Palestinian bringing culture and messages of
peace through art to his people (see my comments,
Life In Israel, April, 2011).
Butler can only visit an “Israeli institution or an Israeli cultural event,” she has said, “in
order
to use the occasion to…” bring attention to the brutality Israel wreaks
on the Palestinians. All this despite Israel’s love and guarantees for
freedom of speech where people are not murdered for their views or their
sexual orientation.
The noxious exhalations of this liege of
miserable intelligentsia are reflections, not of their dutiful
commitment to the sustenance of Israel or the Jewish people, nor the
exercising of their right and obligation to honestly criticize the
democratic state when they believe it wrongheaded, misguided, or worse.
Their opinions do not come from a place of true concern for the fate of
the Jews.
Theirs is not guilt of anti-Semitism by
association, but guilt by collaboration with those who solely wish for
the utter destruction of Israel and the Jews.
The good
Professor Illouz self-identifies with the anti-Semitic Chomsky, et al.
These anti-Israel, anti-Zionist, euthanasic haters, give gravitas to the
BDS movement, the Holocaust deniers, the no acceptance ever of Israel’s
right to exist crazies; they swirl around those with a Jewish identity,
accomplishments, and world renown acclaim, like bees on honey
exuberating in the pother of one-sided anger and hate.
Supporters
and legitimate critics of Israel’s policies and actions through the
democratic process must never stop exposing these people for what they
believe.
On the other hand, I want to adopt as an action plan the Daniel Gordis manifesto that claims
“
It doesn’t matter if they are in Israel or outside, or if they are
Jewish or not. If they are working to end Israel, or to end it as a
Jewish and democratic State, then they are our enemies, plain and
simple. There are enemies who cannot be loved or compromised into
submission, and you need to recognize that…. you need to show us that
you care about Israel more than you care about dialogue with Israel's
enemies.(emphasis added).” I would love to be able to just ignore you.
To paraphrase President Kennedy, I will apologize for calling your kind anti-Semitic if you will apologize for being so.
Labels: Academia, Anti-Semitism, Communication, Crisis Politics, Israel
One bomb in Baghdad targeting Shia pilgrims killed five people
At least 22 people have been killed and tens more injured in a series of explosions across Iraq, officials say.
In the deadliest single attack, seven people were killed in the town of Mussayib, to the south of the capital Baghdad.
At least two people were killed in the southern city of Hilla when a bomb exploded in a busy street.
Violence has decreased in Iraq since its peak in 2006 and 2007, but insurgent attacks remain common.
Five were killed when a car bomb targeted Shia pilgrims in a district of Baghdad.
In the northern city of Kirkuk, the security forces were hit hard by what appears to be a series of co-ordinated attacks.
In one incident, a bomb went off as a police unit dismantled a rocket, killing two policemen and wounding four civilians.
The city has been a source of dispute between the Iraqi government and the Kurdish minority.
In the eastern province of Diyala, at least 10 people were wounded in an attack on a Shia procession.
The latest attacks come in the run-up to the commemoration of
Arbaeen, an important date in the religious calendar for Shia Muslims.
Shia pilgrims have been frequent targets for Sunni extremists.
The violence comes as the government faces multiple crises,
including a protest movement in western Iraq, and a dispute over oil and
territory between Baghdad and the autonomous Kurdish region in the
north, the BBC's Rami Ruhayem in Baghdad reports.
Labels: Conflict, Crisis Politics, Culture, Iraq, Islamism
Failed Syria envoy Brahimi’s mission brings chemical war closer
DEBKAfile
Special Report
December 30, 2012, 9:08 PM (GMT+02:00)
Victim of Syrian army poison gas attack in Homs
The Syrian crisis unbelievably took another turn for the worse
Saturday, Dec. 29: After making no headway with Bashar Assad in
Damascus, the UN-Arab League envoy Lakhdar Brahimi was told in no
uncertain terms by Russian Foreign Minister Sergei Lavrov in Moscow:
“There is no possibility of persuading Syrian ruler Bashar Assad to
leave Syria.” As they spoke, a record 400 people died in hostilities in
the country. The burnt remains of hundreds of people slaughtered by the
army were discovered in a Homs district. And Syrian opposition leaders
have repeatedly preconditioned their acceptance of the Russian
invitation to talks on Assad’s prior exit.
This stalemate is compounded by escalation in the use of two extreme
weapons of war. Since Dec. 12, the Syrian army has been firing home-made
Scud missiles at rebel centers. The US and NATO have responded by
stationing six Patriot batteries manned by 1,000 American, German and
Dutch servicemen, on the Turkish-Syrian border to protect Turkey from
Syrian attack. The inference here is that so long as the Scuds are
confined to targets inside Syria, Western intervention will stop at the
border.
Then on Dec. 26, The Syrian army, under the command of Iranian
officers, began shooting Fateh A-110 high-precision, short-range surface
missiles made in Iran. They were sent to Syria at top speed by an
Iranian airlift flying over Iraq. Syria in fact manufactures a local
version of the Fateh A-110, called M600. But Tehran decided to deliver
the originals to show the world that Assad is not fighting alone and
that Iran’s military support for his regime is solid – not just against
the uprising, but also against NATO, its missiles and the units which
have taken up position in Turkey.
In effect, both sides to the conflict appear to have resorted to a form
of chemical warfare. Western and Middle East military sources report
that, last week, Syrian forces loyal to Assad are thought to have used
in the Homs battle of Dec. 23 grenades containing a gas that paralyzes
lungs and causes extreme infirmity, or even death.
Those sources were careful to point out that the gas was most likely “a
concentrated irritant,” but not one of the deadly chemical weapons
stockpiled by the Assad regime. They were equally careful to avoid
indentifying its origin. debkafile’s
intelligence sources disclose that these gas grenades were especially
developed by Iran’s Revolutionary Guards Corps for use against the
masses which demonstrated against the 2009 presidential elections. The
grenades have now been distributed to pro-Assad Shabiha militias, the
Syrian equivalent of Iran’s brutal al Qods Brigades.
The gas grenades were brought out on Dec. 22, the day after the Syrian
Presidential Guard reported that seven of its number had died in battle
near Damascus as a result of a weapon used by the rebels which “produced
a yellow toxic gas.”
This allegation may have been trumped up to justify the pro-Assad
forces’ use of toxic gas grenades in Homs. Be that as may, both sides
appear to be preparing the ground for chemical warfare. Yet no Western,
or any other external power, including Russia, appears ready to
intervene to put a stop to the latest horror raising its head in the
Syrian conflict, the escalation to chemical warfare - any more than they
prevented its descent to the bombardment of civilians by missiles.
In Amman, the Jordanian information minister Sameeh Maaytah, said
Sunday, Dec. 30, that his government is prepared for any chemical threat
on the kingdom but will not enter into “any alliance” to protect
itself.
Several media attributed the minister’s comment to the visit Israeli
Prime Minister Binyamin Netanyahu paid to Amman last week for talks with
King Abdullah, purportedly about the Syrian chemical weapons threat
they share.
debkafile’s
military sources point out that only the first half of the Jordanian
statement is correct. The other half is as unreal as most of the
comments on the chemical weapons peril heard from Western powers,
Russia, Israel or Arab spokesmen. It is a fact that Jordan has after all
entered into close alliance with NATO, not to mention the US, for
protecting the kingdom. This alliance goes forward on six tracks:
1. Learning how to treat victims of a potential Syrian chemical attack;
2. Setting up an American-Jordanian headquarters in Amman for
coordinated operations against this threat, similar to the joint outfits
the US has established in Israel and Turkey. The Americans have
imported to Jordan a military field hospital specializing in the
treatment of chemical warfare victims;
3. Since last summer, US Army Green Berets, which specialize in chemical warfare, have been training Jordanian troops;
4. Czech and Polish military units, expert in chemical and biological
warfare, are also in the Hashemite kingdom. They are not only
teaching Jordanian units how to combat chemical warfare, but also Syrian
rebels;
5. US and Jordanian special units are standing ready for orders to
enter Syria and attack the sites of the chemical weapons positioned for
shooting into Jordan and Israel;
6. The Jordanian army units deployed between the areas around Amman and
close to the northern Jordanian border with Syria were issued last week
with anti-contamination masks and suits.
All in all, the United States and NATO have prepared Jordan
exhaustively for a possible Syrian chemical weapons attack. If this
happens, some intelligence sources estimate Israel or Turkey may be
targeted next. Given the Syrian conflict’s sequential plunge into
unspeakable atrocities, Israel cannot count on being exempt from a
poison weapons attack - even before its Jan. 22 general election.Labels: Chemical warfare, Conflict, Israel, Jordan, Revolution, Syria, United States
French paper to publish comic book life of Prophet Mohammed
Sunday, 30 December 2012
French satirical weekly Charlie Hebdo's editor, Stephane
Charbonnier, presents to journalists the front cover a satirical book
containing several cartoons depicting Prophet Muhammed. (AFP)
By AFP
Paris
A French weekly known for publishing cartoons of the Prophet
Mohammed to the ire of conservative Muslims said Sunday it plans to
release a comic book biography of Islam’s founder that will be
researched and educational.
Satirical newspaper Charlie Hebdo
has on several occasions depicted Islam’s prophet in an effort to defend
free speech and defy the anger of Muslims who believe depicting
Mohammed is sacrilegious.
“It is a biography authorized by Islam since it was edited by Muslims,”
said Charlie Hebdo’s publisher and the comic’s illustrator, who goes by
the name Charb.
“I don’t think higher Muslim minds could find anything inappropriate,” Charb said.
The biography will be published Wednesday and was put together by a Franco-Tunisian researcher known only as Zineb, Charb said.
The publisher said the idea for the comic book came to him in 2006 when a
newspaper in Denmark published cartoons of Mohammed, later republished
by Charlie Hebdo, drawing angry protests across the Muslim world.
“Before having a laugh about a character, it’s better to know him. As
much as we know about the life of Jesus, we know nothing about
Mohammed,” Charb said.
In September Charlie Hebdo published cartoons of a naked Mohammed as
violent protests were taking place in several countries over a
low-budget film made in the United States that insults the prophet.
In 2011 Charlie Hebdo’s offices were hit by a firebomb and its website
pirated after publishing an edition titled “Charia Hebdo” featuring
several Mohammed cartoons.
Charb, who has received death threats, lives under police protection.
Labels: Communication, France, Islam, News Media
Italian Nobel laureate Rita Levi-Montalcini dies
BBC News online - 30 December 2012
Levi-Montalcini continued to work into her old age
The Italian Nobel prize-winning neurologist Rita Levi-Montalcini has died at the age of 103.
Miss Levi-Montalcini lived through anti-semitic
discrimination under fascism to become one of Italy's top scientists and
most respected figures.
She won acclaim for her work on cells, which furthered understanding of a range of conditions, including cancer.
In 1986 she shared the Nobel prize for medicine with biochemist Stanley Cohen for research carried out in the US.
Her niece, Piera Levi-Montalcini, told La Stampa newspaper that she had died peacefully "as if sleeping" after lunch.
Her aunt had continued to carry out several hours of research every day until her death, she said.
Rita Levi-Montalcini was born in 1909 to a wealthy Jewish family in the northern city of Turin, where she studied medicine.
But after she graduated in 1936 the fascist government banned
Jews from academic and professional careers, and Miss Levi-Montalcini
set up a makeshift laboratory in her bedroom, experimenting on chicken
embryos.
"She worked in primitive conditions," Italian astrophysicist
Margherita Hack told Italian TV. "She is really someone to be admired."
Miss Levi-Montalcini's family lived underground in Florence
after the Germans invaded Italy in 1943. She later worked as doctor for
the allied forces that liberated the city, treating refugees.
From 1947 she was based for more
than 20 years in the US, at Washington University in Saint Louis,
Missouri. There she discovered nerve growth factor, which regulates the
growth of cells.
She later worked at the National Council of Scientific Research in Rome.
Her research was recognised to have advanced the
understanding of conditions including tumours, malformations and senile
dementia.
In 2001 she was nominated to the Italian upper house of
parliament as a senator for life, an honour bestowed on some of Italy's
most distinguished public figures.
She was an ambassador for the Rome-based UN Food and
Agriculture Organisation, and founded the Levi-Montalcini Foundation,
which carries out charity work in Africa.
Miss Levi-Montalcini never married, saying her life had been "enriched by excellent human relations, work and interests".
In a 2009 interview she said: "At 100, I have a mind that is superior - thanks to experience - than when I was 20."
Italian Prime Minister Mario Monti praised Miss
Levi-Montalcini's "charismatic and tenacious" character and her lifelong
battle to "defend the battles in which she believed".
Labels: Italy, Judaism, Medicine, Science
President Chavez, 58 is due to be sworn in for his new term on 10 January
Venezuelan President Hugo Chavez has suffered "new complications" after a cancer operation in Cuba, his vice-president has said.
In a televised address from Cuba, Nicolas Maduro said Mr Chavez continued to be in a "delicate state".
Mr Chavez underwent his fourth cancer operation on 11 December in Cuba but suffered a respiratory infection.
The president - who has been in power since 1999 - won another term in October's election.
Mr Maduro did not give details about Mr Chavez's condition
but said the latest complications were connected to the respiratory
infection.
"We have been informed of new complications that arose as a
consequence of the respiratory infection we already knew about," he
said.
"The president gave us precise instructions so that, after
finishing the visit, we would tell the (Venezuelan) people about his
current health condition.
"The state of health of President Chavez continues to be delicate."
He added that the treatment was "not without risk."
Nicolas Maduro, second right, made the televised address from Havana
Mr Maduro, appearing solemn, spoke alongside Mr Chavez's eldest
daughter, Rosa, his son-in-law Jorge Arreaza, and Venezuelan Attorney
General Cilia Flores.
The vice-president said he would remain in Havana "for the coming hours" but did not specify how long.
Late on Sunday, Venezuela's Information Minister Ernesto
Villegas said a government-organised New Year's Eve concert in central
Caracas had been cancelled and he urged Venezuelans to pray for
President Chavez.
The BBC's Sarah Rainsford in Havana says it is now three weeks since Hugo Chavez has been seen or heard from in person.
There continues to be huge secrecy surrounding his precise condition, she says.
There are also many questions about what will happen on 10
January when Mr Chavez is due to be re-inaugurated, our correspondent
adds.
National Assembly head Diosdado Cabello recently said that
the swearing-in ceremony would be delayed in the case of Mr Chavez's
absence.
However, opposition leaders say postponing the inauguration would be unconstitutional.
The constitution states that if there is an "absolute absence" of the president, elections must be held within 30 days.
Mr Chavez has said that, should his health fail, Venezuelans should vote for Mr Maduro in fresh elections.
Officials have never disclosed the type or severity of Mr Chavez's cancer, which was first diagnosed in June 2011.
More on This Story
Related Stories
Labels: Chaos, Crisis Politics, Culture, Venezuela
Syria’s Assad fears sleeping every night in same bedroom: report
Sunday, 30 December 2012
A portrait of Syrian President Bashar al-Assad burns during clashes between rebels and Syrian troops in near Aleppo. (AFP)
By Al Arabiya with Agencies
Syrian President Bashar al-Assad seems to be developing a highly
cautious nature after reports revealed that he sleeps every night in a
different bedroom and has restricted control over food preparation
driven by his fear of being assassinated.
The Syrian president who had vowed in his last television appearance to
“live and die” in Syria, is now “restricting contacts to a small circle
of family members and trusted advisers,” the Washington Post quoted U.S.
and Middle Eastern officials as saying on Saturday.
The reports said Assad has been sleeping in different bedrooms every
night and has stopped going outdoors during daylight, all seen as
indicators that the president is becoming highly alert on security, “out
of fear that he will be hit by a sniper’s bullet or other fire,” the
newspaper reported.
“His movements suggest a constant state of fear,” a Middle Eastern
official told the Washington Post on condition of anonymity to discuss
sensitive intelligence.
Russia acknowledged on Saturday that al-Assad will not be persuaded to
quit but insisted there is still a chance of finding a political
solution to the 21-month conflict.
International peace envoy Lakhdar Brahimi warned Syria was facing a
choice between "hell or the political process" after talks with Russian
Foreign Minister Sergei Lavrov on his end-of-year bid to accelerate
moves to halt a conflict that monitors say has now killed more than
45,000 people.
The talks came amid emerging signs that Russia was beginning to distance
itself from Assad's government and urgent efforts by Brahimi to
resurrect a failed peace initiative that world powers agreed to in
Geneva in June.
"It is really indispensible that the conflict finishes in 2013 and really the beginning of 2013," the envoy said.
Lavrov said both he and Brahimi agreed there was hope for a solution as long as world powers put pressure on both sides.
"The confrontation is escalating. But we agree the chance for a political solution remains," he said.
Moscow has been under intense pressure to urge the leadership of its
last Middle East ally to accept a face-saving agreement that would see
the rebels assume gradual command as the fighting reaches Damascus
itself.
Yet analysts have questioned the actual sway the Kremlin has over Assad,
and Lavrov appeared to betray a hint of frustration when revealing that
Assad had this week told Brahimi that he does not intend to leave.
"Regarding Bashar al-Assad, he repeatedly said, both publically and in
private... that he is not planning to leave, that he will remain in his
post," Lavrov said.
"There is no possibility to change this position."
Labels: Crisis Politics, Diplomacy, Russia, Security, Societal Failures, Syria
Al Qaeda Wants to Kill Another US Ambassador
Al
Qaeda terrorists in Yemen offer $160,000 in gold for killing the US
ambassador, three months after the envoy to Libya was murdered.
By Tzvi Ben Gedalyahu-
Arutz Sheva 7
First Publish: 12/30/2012, 7:16 PM
Motorcycle hit in drone strike in Yemen
Reuters
Al Qaeda terrorists in Yemen offer $160,000 in gold for killing the
US ambassador, three months after the US envoy to Libya was murdered.
The US State Dept. presumably will take the matter more seriously than it did when senior officials ignored events
leading up to the brutal killing of Christopher Stevens on September 11.
The al-Malahem terrorist website also offered $23,000 to anyone who murders an American soldier, but the offer is valid
for only six months.
The website posting followed a US drone strike in Yemen that killed
three AQ terrorists, including a senior Al Qaeda member, Saleh Mohammed
al-Ameri. The bounties were set to "inspire and encourage our Muslim
nation for jihad," the statement said.
A day earlier, five others were killed, and the US army carried our
four drone strikes during the week, although the military followed its
usual practice of not confirming the counterterrorist operations. More
than 40 aerial strikes have been carried out this year in Yemen,
according to the
Long War Journal.
Saturday’s attack on a
vehicle "completely obliterated" and the bodies left charred,” according to local tribesmen quoted by BBC.
Al Qaeda plotted in 2008 and 2010 to blow up American airliners, and
the Obama administration is fighting a tough battle to keep the Yemeni
government in power while Al Qaeda terrorists have effectively taken
over the southern part of the country.
However, the US drone attack strategy has also killed many innocent
civilians and has stoked anti-American hatred among many Yemeni
tribesman
The Arab Spring revolution in 2011 left the country in shambles as
competing tribes fought for control and terrorists took advantage of the
vacuum of the power to gain territory.
The
Los Angeles Times wrote last week, “The danger in the
drone program is the potential for U.S. intelligence and airstrikes to
be manipulated by Yemenis seeking to weaken the competing clans and
political factions.
“For example, Obama and his top generals felt misled in 2010 when
Obama signed off on an airstrike against a senior militant that killed
six people, including the deputy governor of Mareb province. The strike
was based entirely on intelligence provided by the Yemenis, who had not
told the U.S. that the governor would be there, a former senior U.S.
official said.”
It quoted Ahmed al Zurqua, an expert on Islamic militants, Saudi
Arabia saying, “The drones have not killed the real Al Qaeda leaders,
but they have increased the hatred toward America and are causing young
men to join Al Qaeda to retaliate.”
More on this topic
Labels: Culture, Islamism, Political Realities, Terrorism, United States
Egypt to Pursue a Relationship with Hizbullah
Egypt will pursue a relationship with Hizbullah as a “real political and military force”, says Egyptian ambassador.
By Elad Benari-
Arutz Sheva 7
First Publish: 12/30/2012, 5:35 AM
Hizbullah
Flash 90
Egypt will pursue a relationship with the Hizbullah terror group as a
“real political and military force” on the ground in Lebanon, the
Egyptian ambassador to Lebanon told the Lebanese newspaper
Daily Star on Saturday.
Speaking after Egypt’s Muslim Brotherhood-backed new constitution was
signed in to law, Ambassador Ashraf Hamdy said Egypt would keep
contacts “tight,” even with its enemies.
“We are stretching our hand out in
the proper, balanced way to all regional powers, but of course, we will continue to develop our foreign policy
according to our interests,” he said.
“You cannot discuss politics in Lebanon without having a relationship
with Hizbullah. It is a real force on the ground. It has a big
political and military influence in Lebanon,” the ambassador told
The Daily tar.
Hamdy denied reports that a Hizbullah delegation had visited Egypt
but said he had met with members of the group's "political bureau" in an
effort “to understand each other better.”
“In discussions we said we want Hizbullah to remain as a political
force in Lebanon acting in the interests of the Lebanese first and not
others,” Hamdy continued.
“Resistance in the sense of defending Lebanese territory ... That’s
their primary role. We ... think that as a resistance movement they have
done a good job to keep on defending Lebanese territory and trying to
regain land occupied by Israel is legal and legitimate,” he added.
Hizbullah has been designated as a terror organization by the U.S. State Department since 1997. The U.S. has
imposed sanctions on the organization's leader, Hassan Nasrallah, and other officials.
The U.S. Senate has
passed a resolution calling on European countries to designate Hizbullah as a terrorist organization as well.
The group is openly backed by the Iranian regime and, while there
have been no diplomatic ties between Egypt and Iran since 1979, the
country's current president Mohammed Morsi appeared to be getting closer
to the Islamic Republic.
Morsi, who is a member of the Muslim Brotherhood, visited Iran in August, where he met
President Mahmoud Ahmadinejad. However, Morsi's spokesman later said the meeting
did not address the issues of bilateral relations or raising the
level of diplomatic representation between the two countries.
The Iranian website
PressTV reported that Ahmadinejad and Morsi
described the two countries as “strategic allies” during the meeting.
More on this topic
Labels: Culture, Egypt, Hezbollah, Islamism
Gaza construction convoy crosses from Egypt
The trucks passed through the Rafah crossing into Gaza
Egypt has allowed a shipment of construction materials to enter the Gaza Strip from its territory for the first time since 2007.
A convoy of trucks carrying thousands of tonnes of supplies
donated by the Gulf state of Qatar entered Gaza via the Rafah border
crossing on Saturday.
Egypt had previously followed import restrictions imposed by Israel.
However, Israel has eased its blockade as part of last month's ceasefire deal with the Islamist group Hamas.
Many goods are smuggled from Egypt through a network of underground tunnels into Gaza, which is governed by Hamas.
An Egyptian security official quoted by AP news agency said
the shipment had been made in consultation with Israeli officials who
were in Cairo on Thursday.
Qatar has pledged more than $400m (£250m) to finance
reconstruction in Gaza and improve crumbling housing, schools, a
hospital and roads.
A Hamas official said it was a positive step.
"We hope that Egypt will open this crossing permanently for
goods so our people can meet their needs," said Ehab al-Ghsain, head of
the Hamas government's media office.
Some 170 Palestinians and six Israelis were killed in an eight-day conflict between Hamas and Israel in November.
Earlier this month, Hamas celebrated its 25th anniversary in
Gaza with a rally attended by exiled political leader Khaled Meshaal.
Hamas won elections in Gaza in 2006 and came to power a year later after ejecting the rival Fatah faction.
Labels: Egypt, Gaza, Hamas
Pakistan militants kill at least 20 kidnapped troops
BBC News online - 29 December 2012
The Pakistani tribal police force operate in the semi-autonomous tribal region
Militants in Pakistan have killed at least 20 of the paramilitaries they seized from checkpoints near Peshawar, officials say.
Two men are said to have escaped. One is reportedly in a critical condition.
The troops, from the tribal police force, are reported to
have been shot by their captors, who are thought to be from the
Pakistani Taliban.
The men were seized following attacks on three checkpoints south of Peshawar, close to the border with Afghanistan.
About 200 armed militants had overrun two of the positions on
Thursday, seizing the troops, taking weapons and setting fire to the
buildings.
Two tribal police officers were killed in the attacks.
The Pakistani military launched an operation to recover the men and convened a meeting of local tribal elders.
A local government official, Naveed Akbar, said the bodies
had been recovered about 4km (3 miles) from where the troops had been
abducted.
It is the third attack on targets around Peshawar this month.
Suicide bombers launched a raid on the city's airport two weeks ago,
killing four people.
Last Saturday a senior politician of the Awami National Party
was killed in an attack on a political rally. Seven others died in the
blast.
On Friday the head of the Pakistani Taliban, Hakimullah
Mehsud, released a video in which he offered to open negotiations with
Islamabad.
But he refused to lay down his weapons and demanded that Pakistan break ties with the United States before talks could start.
The Pakistani Taliban operates mainly from within the semi-autonomous tribal region along the border with Afghanistan.
The Pakistani government says more than 35,000 people have
been killed in attacks blamed on Islamic militants since the attacks of
September 11.
It launched an offensive against the group in 2009 in the
Swat Valley and South Waziristan, since when attacks by the Pakistani
Taliban have decreased.
Labels: Conflict, Culture, Pakistan, Taliban
The Future of Medicine Is Now
The Wall Street Journal
From cancer treatments to new devices to gene
therapy, a look at six medical innovations that are poised to transform
the way we fight disease
Reporter Ron Winslow talks to WSJ weekend
Review editor Gary Rosen about astonishing medical advances that are
finally moving from research and prototypes to practical treatments.
In our era of
instant gratification, the world of medicine seems like an outlier. The
path from a promising discovery to an effective treatment often takes a
decade or more.
But from that process—of fits and
starts, progress and setbacks and finally more progress—grow the
insights and advances that change the course of medicine.
A decade ago, the completion of the
Human Genome Project sparked optimism that cures for debilitating
diseases were just around the corner. Cures still generally elude us,
but now the ability to map human DNA cheaply and quickly is yielding a
torrent of data about the genetic drivers of disease—and a steady stream
of patients who are benefiting from the knowledge. On other fronts,
technology is putting more power in the hands of patients, and
researchers are learning to combat disorders by harnessing the body's
own ability to heal and grow.
Foundation Medicine
A test developed by Foundation
Medicine Inc. analyzes tumor DNA to help find targeted treatment options
for patients with cancer.
Advances
bring other challenges, including how to pay for them. Meanwhile, the
complex biology that stymies gains for some patients sets goals for new
advances.
Here are six of today's potentially transformative trends.
Growing a Heart
Surgeons at
Boston Children's Hospital have developed a way to help children born
with half a heart to essentially grow a whole one—by marshaling the
body's natural capacity to heal and develop.
About 1,000 babies are born in the U.S.
each year with a condition called hypoplastic left-heart syndrome, the
result of a genetic anomaly that leaves them without a functioning left
ventricle, the heart's main pumping chamber. Without a surgical repair,
the defect is almost always fatal.
Jennifer S. Altman for The Wall Street Journal
A new surgical strategy helped 9-year-old Alexa Rand's body to essentially grow half a heart into a whole one.
The
standard treatment is a series of three open-heart operations to reroute
circulation so that the right ventricle can take over pumping blood to
the body's organs and extremities. But the right ventricle "is meant to
handle low-pressure blood flow to the lungs," says Sitaram Emani, the
surgeon heading the effort on the new approach. "Now you're asking it to
do the work of a high-pressure system and to do that work for many
years. Eventually it fails." That's one reason why 30% of patients or
more don't survive to adulthood.
Dr. Emani and his colleagues devised a
complex strategy to open obstructed valves and repair other
malformations to direct blood flow to the left ventricle instead of away
from it. That triggers biological processes that promote the heart's
growth.
Last month, after using the approach on
34 carefully selected patients over the past decade, the doctors
reported in the Journal of the American College of Cardiology that 12
now have two working ventricles. One of them, 9-year-old Alexa Rand of
Kings Park, N.Y., whose treatments began in utero, is thriving. She
sings, dances and surprises doctors with how long she can walk on a
treadmill, says her mother, Rosamaria Rand.
The main drawback: The strategy
requires one more surgical procedure, on average, and significantly more
days in the hospital than the conventional surgery. The hope is, Dr.
Emani says, that the long-term benefits will outweigh the extra hospital
time.
—Ron Winslow
DNA Sequencing for Routine Checkups
At
a genetics conference in November, Oxford Nanopore Technologies
unveiled the first of a generation of tiny DNA sequencing devices that
many predict will eventually be as ubiquitous as cellphones—it's already
the size of one.
Since the first sequencing of the human
genome was completed in 2003 at a price tag of over $2 billion, the
speed, price and accuracy of the technology have all improved.
Illumina Inc.
ILMN -1.19%
has dropped its price for individual readouts to $5,000; earlier this
year, Life Technologies introduced a sequencer it says can map the human
genome for $1,000. The smallest machine is now desktop-size.
But
nanopore sequencing devices, which are designed to be even smaller and
more affordable, could speed efforts to make gene sequencing a routine
part of a visit to the doctor's office. DNA molecules are exceedingly
long and complicated; that makes them hard to read. Nanopore technology
measures changes in the molecules' electrical current as the DNA is
threaded in a single strand through tiny holes called "nanopores"
created in a membrane.
So far, U.K.-based Oxford has released
the results of sequencing a virus genome with this technique. The
company hasn't provided data, however, showing that the sequencers can
analyze the much larger human genome. A spokeswoman for Oxford says the
company is working hard toward being able to sell devices, including one
that is expected to cost under $1,000, though it doesn't yet have a
launch date.
Amit Meller—an associate professor at Boston University,
a scientific adviser at Oxford and the co-founder of Noblegen
Biosciences—is at work on another nanopore device that he says would use
fluorescent signals to read the DNA information. His company is still a
number of years away from a prototype, but Dr. Meller says the goal is
to speed up sequencing even more—with results in a few hours, not the
current weeks or days, at a cost of less than $100.
—Amy Dockser Marcus
Matching a Tumor to a Drug
Our
growing understanding of the workings of the human genome is posing a
new challenge: How to use that data to change the course of disease.
Consider cancer. As seen through a gene-sequencing machine, some cancers
can appear as at least a dozen different genetic diseases, some of
which have been shown to respond uniquely to a specific drug. But how do
cancer doctors quickly match a patient's tumor with a drug that targets
it?
One answer is a
test developed by Foundation Medicine Inc., a Cambridge, Mass., startup
whose scientific founders include one of the leaders of the Human
Genome Project. The test, officially launched last June, enables doctors
to test a tumor sample for 280 different genetic mutations suspected of
driving tumor growth.
This changes "everything in terms of
how we approach patients with cancer," says David Spigel, director of
lung-cancer research at the Sarah Cannon Research Institute in
Nashville, Tenn. He used the test in one patient with advanced disease
and few apparent options. She turned out positive for an alteration in a
gene targeted by several drugs currently in development. She was signed
up for one of the studies. A short time later, "she's like a new
person," he says. "She's off pain medicines. She gained her weight
back."
Michael Pellini, Foundation's chief executive officer,
says that more than 600 oncologists have requested the test, which lists
for $5,800. So far, he says, about 70% of cases have turned up a
mutation that is potentially targeted by a drug on the market or in a
clinical trial.
In one recent case, Dr. Pellini says, a
sample from a woman with advanced pancreatic cancer yielded a response
for "her2," an alteration associated with a certain form of breast
cancer. She was treated and her cancer responded to the breast-cancer
drug Herceptin. Few oncologists would think to look for her2 in a
patient with pancreatic cancer, he says.
—Ron Winslow
Letting Your Body Fight Cancer
Few advances in cancer care are generating more enthusiasm than harnessing the power of the immune system to fight the disease.
Tom Stutz is one reason why. Last April, the 72-year-old
retired lawyer was confined to a wheelchair, struggling for every
breath, and required help with simple tasks such as eating, all because
of a previously diagnosed skin cancer that had spread to his lungs and
liver. "I was ready to check out, to be honest," he says.
That month, he began taking an
experimental drug known as MK3475. Six weeks later, he started feeling
better. Today, Mr. Stutz has jettisoned the wheelchair and regularly
walks a 3.5-mile loop near his home in Los Angeles. "I feel terrific,"
says Mr. Stutz, who learned after a checkup in the fall that his tumors
had shrunk by about 65% so far.
For decades, cancer researchers have
wondered why the immune system typically doesn't treat tumor cells as
invaders and target them. Part of the mystery was recently solved:
Tumors protect themselves by hijacking the body's natural brake for the
immune system.
MK3475, being developed by Merck &
Co., is among a new category of drugs that release the brake, unleashing
an army of immune cells to hunt down the cancer. A recent report from a
trial in which Mr. Stutz participated said that of 85 patients who took
the drug, 51% saw their tumors significantly shrink; in eight cases,
the tumors couldn't be detected on imaging tests.
Still, not everyone was helped. And
unleashing the immune system can put normal cells in harm's way: In
studies of MK3745 and similar drugs, some patients developed serious
side effects related to immune-system response, including a small number
who died.
But interest in the approach is strong.
Bristol-Myers Squibb Corp.'s
BMY -0.75%
drug Yervoy, approved by the Food and Drug Administration in 2011, is
the first of its kind to reach the market. The company has others in
development.
GlaxoSmithKline
GSK.LN -0.22%
PLC and
AstraZeneca's
AZN.LN -0.46%
MedImmune are among others exploring ways to activate the immune system against cancer.
One
reason for the excitement is that most "solid" tumors—colon, lung,
breast, prostate—use the same or a similar mechanism to hide from the
immune system. Obstructing that mechanism may have a broad impact across
a variety of malignancies.
—Ron Winslow
Health in the Palm of Your Hand
There's
a good chance that you already own one of the most ubiquitous
health-care innovations: a smartphone. Last month, the FDA cleared a new
iPhone add-on that lets doctors take an electrocardiogram just about
anywhere. Other smartphone apps help radiologists read medical images
and allow patients to track moles for signs of skin cancer.
"I see the smartphone as one piece of
how we're going to try to get health costs under control," says David
Albert, the Oklahoma City-based inventor of the just-approved AliveCor
electrocardiogram application.
At $199, AliveCor consists of a case
that snaps onto the iPhone, with electrodes on the back. It reads heart
rhythms and relays the recording to an iPhone app, allowing physicians
to read the data. Dr. Albert says a $99 version should be available soon
that will let patients capture their own heart data, documenting
sometimes-fleeting arrhythmias when they feel symptoms or tracking the
success of lifestyle changes at curbing heart troubles.
Doctors say that mainstream EKG
machines provide more information but the iPhone version is sufficient
for many diagnostic needs. "When I go to [the] clinic, I use it in place
of an EKG all the time," says Leslie Saxon, chief of the University of
Southern California's heart-rhythm department, which has conducted
research using AliveCor's device.
The FDA has cleared a handful of apps,
beginning with an iPad and iPhone-based medical imaging reader in 2011.
The smartphone lets us "bring health care into the home," says Erik
Douglas, CEO of CellScope. His company is developing an iPhone-based
otoscope that would allow parents to upload images of their children's
inner ears when they show signs of infections, with the aim of avoiding
unnecessary doctors visits.
—Christopher Weaver
Rejigging Your Genes
After
years of controversy, gene therapy is poised to become a viable option
for a variety of often life-threatening medical conditions, especially
those resulting from a single defective gene. Last month, the European
Union approved Glybera for treatment of a rare genetic disease, making
it the first gene-therapy medicine approved in the Western world. The
approval comes amid a flurry of research showing broader promise for the
approach in a range of disorders, from a rare form of blindness to
hemophilia to heart failure.
Though outright cures are still
elusive, gene therapy "is beginning to emerge as a meaningful clinical"
strategy, says Stephen J. Russell, director of molecular medicine at the
Mayo Clinic in Rochester, Minn.
Gene therapy's tantalizing attraction
is that a single treatment has the potential to cure lethal diseases by
enabling normal genes to take over for defective ones. The treatment
involves loading a functional gene onto a fragment of a deactivated
virus that transports the gene to a cell's nucleus, where it is intended
to take over.
The idea suffered major setbacks in
1999 when a U.S. teenager died in a gene-therapy trial and again soon
after when several children in Europe developed leukemia after receiving
gene therapy.
The episodes prompted criticism that
researchers had moved too quickly. Scientists returned to the
laboratory, hoping to develop better delivery vehicles and to improve
both the safety and efficacy of the treatments.
Bluebird Bio, a Cambridge, Mass.,
gene-therapy startup, expects to launch studies next year for two rare
genetic diseases: childhood adrenoleukodystrophy, or ALD, an inherited
and lethal neurological disorder; and beta thallasemia, which causes the
destruction of red blood cells and leads to life-threatening anemia.
Its technique involves extracting a patient's own bone-marrow cells,
isolating certain stem cells, and delivering the gene therapy before
returning the cells to the body.
Four boys in Paris with ALD have been
successfully treated, says Nick Leschly, Bluebird's president and chief
executive officer, including two treated nearly six years ago. They are
now in their teens and would otherwise likely have died before age 10,
he says.
Other gene-therapy efforts include
Novartis SA's
NOVN.VX -0.43%
partnership with the University of Pennsylvania on a treatment for
cancer, GlaxoSmithKline's alliance with Italian scientists for a range
of disorders, and Celedon Corp.'s clinical trial of a gene therapy in
patients with advanced heart failure.
—Ron Winslow
A version of this article appeared December
29, 2012, on page C2 in the U.S. edition of The Wall Street Journal,
with the headline: No Headline Available.
Labels: Biology, Health, Science